The Physiological Role of Testosterone in the Male Body.

The problem of declining fertility and potency particularly acute rises in our society today, because people are very intense hard life full of stress, the effects of environmental factors, it is all happening against the background of malnutrition, bad habits and physical inactivity. We can not ignore the effects of this for the sole reason that they accumulate slowly, silently creeping gradually deteriorating health.

Back in the mid-19th century, Charles Brown, Sekar, the great French scientist, he observed himself not only an increase in potency at the age of 75 years, but the telltale signs of a significant rejuvenation of the organism as a whole, it has emerged that after injecting extracts from the testes of monkeys. It was the beginning of a close examination of sex hormones in science, today it is these effects of testosterone are the subject of attention of gerontologists concerned with the problem of active longevity extension of humanity.

Science has long known about the hierarchy of the regulatory systems of the body: any disruption in the body begins with the brain: on the bark or the hypothalamic-pituitary region. The above mentioned negative factors directly affect the higher echelons of regulation.

Hence the limitation of any hormone replacement therapy: it makes an artificial shortage of substances and do not address the root cause of the problem occurred. A failure by reducing the potency and fertility begins with pituitary region: reduced secretion of luteinizing hormone, which controls the production of testosterone by the testes. Meanwhile, testosterone acts on the whole organism.

Let us examine the physiological role of testosterone.
Male sex hormones (androgens) to have a biological effect on almost all body tissues, initiating the processes of synthesis and construction. That is all androgens, including testosterone, is an anabolic hormone.

Thus, the main effects of testosterone are:
-Stimulation of genital organs and central nervous structures (the hypothalamus and pituitary glands) of male pattern;
-Stimulation of body hair distribution of male pattern;
-Stimulation of linear growth of the body, stimulating muscle development, the development of the larynx and thickening of the vocal cords;
-Stimulation of red blood cell formation and distribution of adipose tissue in male pattern;
-Stimulation of the formation of sperm cells with FSH and LH (pituitary) the entire process of sperm formation takes about 74 days, after which the sperm is transported through the epididymis to the urethra close within 12-21 days;
-To establish the male psyche and sexuality.


The secretion of testosterone is not constant, but occasionally, that is the cause of significant fluctuations in its level in the blood. Maximum secretion occurs between 2:00 and 6:00 o'clock in the morning, and the minimum - at about 13:00. In the body there are only 2% of circulating free testosterone. About 68% of testosterone are associated with the transport of blood protein albumin, and another 30% - with a specific binding globulin sex hormones.

In the peripheral tissues by the enzyme testosterone 5-alpha-reductase is converted to its active metabolite most - dihydrotestosterone.

Decomposes testosterone in the liver and through urine and bile excreted.
The normal level of testosterone in healthy men in the first half of the day is 12-40 nmol / l.

The testosterone level less than 10nmol / l probably testifies for the deficiency of the hormone. Border data (between 10-12 nmol / l) requires clarification and further examination.

Together with the definition of the level of free testosterone is usually necessary to determine the level of binding globulin sex hormones (SHBG).

The decision to undergo a course of anabolic steroids - it is always a very important decision. Absolute contraindications to the use of steroids are prostate cancer and breast cancer. This is due to the fact that these tumors are generally hormone-dependent, i.e., arising due to hormone imbalance in the body, and their high performance. Steroid use in such cases leads to a sharp deterioration and prognosis.